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Welcome to the Mission Metabolic Health Blog
Here you'll find articles written by Dr. Cassleman, covering a wide range of topics related to metabolic health, weight loss, hormone therapy, and preventative medicine. Each post is grounded in medical expertise and real-world patient care—designed to educate, inspire, and support you on your health journey.


Understanding Lipoprotein(a): A Commonly Overlooked Heart Risk Factor
What Is Lipoprotein(a)? Lipoprotein(a), often abbreviated as Lp(a), or “LP little a” is a type of cholesterol particle found in your...
Dr. Sean Cassleman
4 days ago2 min read


Why a Standard Lipid Panel May Not Be Enough
Cardiovascular health remains a cornerstone of longevity. Unfortunately, traditional approaches to lipid management often overlook...
Dr. Sean Cassleman
Jun 233 min read


Frailty: When Resilience Fades
Not long ago, a close friend shared a heartbreaking story about her mother. Once independent and lively, her mother’s health began to...
Dr. Sean Cassleman
Jun 103 min read


Cardiovascular risk from TRT? What It Means for Metabolic Health
For many years there have been concerns about the safety of testosterone replacement in men from a cardiovascular standpoint. The...
Dr. Sean Cassleman
Apr 292 min read


Osteoporosis and Menopausal Hormone Therapy
Menopause significantly accelerates bone loss, increasing the risk of osteoporosis—a condition affecting 1 in 2 postmenopausal women globally.
Dr. Sean Cassleman
Apr 162 min read


The Destructive Impact of Low Testosterone on Metabolic Health
Low testosterone levels can have a destructive impact on men's health, particularly in relation to metabolic function. At Mission...
Dr. Sean Cassleman
Feb 213 min read


Osteoporosis Prevention: Why Aren’t We Talking About Exercise First?
Despite good intentions and sometimes good outcomes I commonly see our approach to osteoporosis in medicine fall short. This is typically...
Dr. Sean Cassleman
Feb 212 min read


Osteoporosis Screening: A Call for Earlier Action
As a physician, I see far too many patients diagnosed with osteoporosis only after they’ve already suffered significant bone loss. The...
Dr. Sean Cassleman
Feb 212 min read


Menopausal Hormone Therapy (MHT)/(HRT), is it worth considering?
This article will explore the positive effects of HRT on body composition, bone health, lipids, insulin resistance, sex life, and the manage
Dr. Sean Cassleman
Nov 5, 20244 min read


GLP-1 Weight Loss Medications: Exploring the Other Options
Listening to current media it may seem like weight loss drugs did not exist before the advent of GLP-1 medication, but there are other...
Dr. Sean Cassleman
Jun 10, 20243 min read


The Dangers of Muscle Mass Loss
Muscle mass loss, also known as sarcopenia, is a serious condition that can have far-reaching consequences on overall health and...
Dr. Sean Cassleman
Jun 10, 20242 min read


Why it's important to have a doctor following you closely when you are on GLP-1s
(Semaglutide, Ozempic, Wegovy, Liraglutide, Saxenda, Tirzepitide, Mounjaro, Zepbound) Glucagon-like peptide-1 (GLP-1) receptor agonists...
Dr. Sean Cassleman
Jun 10, 20243 min read


We Shouldn’t Have to Have this Conversation
OK, let's get it out of the way. Where do we at MMH fall on the endless conversation about the root causes of Obesity. Even though our...
Dr. Sean Cassleman
Jun 10, 20243 min read


Optimizing Protein, Just for Meatheads?
At your local fitness center or in the halls of MMH for that matter, you may hear a couple of gym rats discussing the merits of different...
Dr. Sean Cassleman
Jun 10, 20242 min read
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